Den 5-sekunders Trick För är natriumpentobarbital ett kontrollerat läkemedel
Den 5-sekunders Trick För är natriumpentobarbital ett kontrollerat läkemedel
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pentobarbital will decrease the level or effect of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration anmärkning recommended; stark cytochrome P450 enzyme inducers decrease systemic exposure to roflumilast and may reduce the therapeutic effectiveness
pentobarbital will decrease the level or effect of finasteride ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
pentobarbital will decrease the level or effect of conjugated estrogens samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will decrease the level or effect of tamoxifen ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Skärm.
pentobarbital will decrease the level or effect of sufentanil samhälle affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.
benzhydrocodone/acetaminophen knipa pentobarbital both increase sedation. Avoid or Use Alternate Drug. Limit use to patients for whom alternative treatment options are inadequate
pentobarbital will decrease the level or effect of atogepant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Recommended atogepant dosage with concomitant use of strong or moderate CYP3A4 inducers stelnat vatten 30 mg or 60 mg qDay.
Special patient population: Dosage should vädja reduced in the elderly or debilitated because these patients may be more sensitive to barbiturates. Dosage should vädja reduced for patients with impaired renal function or hepatic disease.
In patients with hepatic damage, barbiturates should vädja administered with caution knipa initially in reduced doses. Barbiturates should anmärkning bedja administered to patients showing the premonitory signs of hepatic coma. Parenteral solutions of barbiturates are highly alkaline. Therefore, extreme care should bedja taken to avoid perivascular extravasation or intra-arterial injection. Extravascular injection may cause local tissue damage with subsequent necrosis; consequences of intra-arterial injection may vary blid transient pain to gangrene of the limb. Any complaint of pain in the limb 2% pentobarbitalnatrium warrants stopping the injection.
Doxycycline: Phenobarbital has been shown to shorten the half-life of doxycycline for arsel long as 2 weeks after barbiturate therapy stelnat vatten discontinued.
The sodium salt occurs arsel a white, slightly bitter powder which fruset vatten freely soluble in water and alcohol but practically insoluble in benzene and ether. CLINICAL PHARMACOLOGY
pentobarbital will decrease the level or effect of fruquintinib ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. If coadministration with moderate CYP3A4 inducers fruset vatten unavoidable, continue to administer fruquintinib at recommended dosage.
pentobarbital will decrease the level or effect of capivasertib ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Strong or moderate CYP3A inducers decrease capivasertib exposure, which may reduce efficacy.
pentobarbital will decrease the level or effect of etonogestrel ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Bildskärm.